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Homeopathy. 2010 Oct;99(4):231-42.Extreme homeopathic dilutions retain starting materials: A nanoparticulate perspective.
Chikramane PS, Suresh AK, Bellare JR, Kane SG. Department of Chemical Engineering, Indian Institute of Technology, Bombay, Adi Shankaracharya Marg, Powai, Mumbai, Maharashtra, India.
Homeopathy. 2010 Oct;99(4):229-30. Abstract Homeopathy is controversial because medicines in high potencies such as 30c and 200c involve huge dilution factors (10⁶⁰ and 10⁴⁰⁰ respectively) which are many orders of magnitude greater than Avogadro's number, so that theoretically there should be no measurable remnants of the starting materials. No hypothesis which predicts the retention of properties of starting materials has been proposed nor has any physical entity been shown to exist in these high potency medicines. Using market samples of metal-derived medicines from reputable manufacturers, we have demonstrated for the first time by Transmission Electron Microscopy (TEM), electron diffraction and chemical analysis by Inductively Coupled Plasma-Atomic Emission Spectroscopy (ICP-AES), the presence of physical entities in these extreme dilutions, in the form of nanoparticles of the starting metals and their aggregates.
Copyright © 2010 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.
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RESEARCH ARTICLE #homeopathy Individualized Homeopathic Treatment and Fluoxetine for Moderate to Severe Depression in Peri- and Postmenopausal Women (HOMDEP-MENOP Study): A Randomized, Double-Dummy, Double-Blind, Placebo-Controlled Trial Emma del Carmen Macías-Cortés1,2*, Lidia Llanes-González3, Leopoldo Aguilar-Faisal1, Juan Asbun-Bojalil1 1 División de Estudios de Posgrado, Escuela Superior de Medicina, Instituto Politécnico Nacional, Distrito Federal, México, 2 Consulta Externa de Homeopatía, Hospital Juárez de México, Secretaría de Salud, Distrito Federal, México, 3 Unidad de Salud Mental, Hospital Juárez de México, Secretaría de Salud, Distrito Federal, México * firstname.lastname@example.org Abstract Background Perimenopausal period refers to the interval when women's menstrual cycles become irreg- ular and is characterized by an increased risk of depression. Use of homeopathy to treat de- pression is widespread but there is a lack of clinical trials about its efficacy in depression in peri- and postmenopausal women. The aim of this study was to assess efficacy and safety of individualized homeopathic treatment versus placebo and fluoxetine versus placebo in peri- and postmenopausal women with moderate to severe depression. Methods/Design A randomized, placebo-controlled, double-blind, double-dummy, superiority, three-arm trial with a 6 week follow-up study was conducted. The study was performed in a public research hospital in Mexico City in the outpatient service of homeopathy. One hundred thirty-three peri- and postmenopausal women diagnosed with major depression according to DSM-IV (moderate to severe intensity) were included. The outcomes were: change in the mean total score among groups on the 17-item Hamilton Rating Scale for Depression, Beck Depres- sion Inventory and Greene Scale, after 6 weeks of treatment, response and remission rates, and safety. Efficacy data were analyzed in the intention-to-treat population (ANOVA with Bonferroni post-hoc test). PLOS ONE | DOI:10.1371/journal.pone.0118440 March 13, 2015 1/24 OPENACCESS Citation: Macías-Cortés EdC, Llanes-González L, Aguilar-Faisal L, Asbun-Bojalil J (2015) Individualized Homeopathic Treatment and Fluoxetine for Moderate to Severe Depression in Peri- and Postmenopausal Women (HOMDEP-MENOP Study): A Randomized, Double-Dummy, Double-Blind, Placebo-Controlled Trial. PLoS ONE 10(3): e0118440. doi:10.1371/ journal.pone.0118440 Academic Editor: Yiru Fang, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, CHINA Received: September 18, 2014 Accepted: January 13, 2015 Published: March 13, 2015 Copyright: © 2015 Macías-Cortés et al. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: Data are available upon request to the Research and Ethics Committee of National Homeopathic Hospital, Mexico City [Dr. Gustavo Aguilar-Velázquez ( email@example.com
Results After a 6-week treatment, homeopathic group was more effective than placebo by 5 points in Hamilton Scale. Response rate was 54.5% and remission rate, 15.9%. There was a sig- nificant difference among groups in response rate definition only, but not in remission rate. Fluoxetine-placebo difference was 3.2 points. No differences were observed among groups in the Beck Depression Inventory. Homeopathic group was superior to placebo in Greene Climacteric Scale (8.6 points). Fluoxetine was not different from placebo in Greene Climac- teric Scale. Conclusion Homeopathy and fluoxetine are effective and safe antidepressants for climacteric women. Homeopathy and fluoxetine were significantly different from placebo in response definition only. Homeopathy, but not fluoxetine, improves menopausal symptoms scored by Greene Climacteric Scale. Trial Registration ClinicalTrials.gov NCT01635218 Protocol Publication http://www.trialsjournal.com/content/14/1/105 . https://www.hri-research.org/wp-content/uploads/2015/03/Mac%C3%ADas-Cort%C3%A9s-2015-Depression-menopause.pdf
In the organic livestock sector antibiotics are preferably replaced by complementary or alternative medicines (CAM), of which homeopathy is the most frequently applied. Homeopathic treatment has significant benefits since there are no residues of homeopathic medicines in animal products, nor does homeopathy generate resistant microorganisms.
The Biological Farming Systems Group at the Wageningen University in the Netherlands recently conducted a research study to investigate if homeopathy might be an alternative to antibiotics in one of the most common illnesses in swine which is neonatal diarrhoea of piglets. This disease leads to weight loss and increased piglet mortality, which has substantial economic consequences. Conventional treatments of Escherichia coli (E. coli) diarrhoea is administration of antibiotics to affected piglets, or preventive vaccination of the sows.
To investigate if E. coli diarrhoea in neonatal piglets could be prevented by homeopathy, the researchers set up a randomised, observer blind and placebo-controlled trial. On a commercial pig farm 52 sows of different parities, in their last month of gestation, were treated twice a week with either the homeopathic agent Coli 30K or placebo. The 525 piglets born from these sows were scored for occurrence and duration of diarrhoea.
Piglets of the homeopathic treated group had significantly less E. coli diarrhoea than piglets in the placebo group (P < .0001). Especially piglets from first parity sows gave a good response to treatment with Coli 30K. The diarrhoea seemed to be less severe in the homeopathically treated litters, there was less transmission and duration appeared shorter.
Advantages at farm level are application of the treatment by the farmer and cost reduction. These advantages and the positive results from this study make the homeopathic agent Coli 30K an attractive potential alternative in the prevention of E. coli diarrhoea. This study also suggests that homeopathic treatment in livestock may help the European citizen be protected from pharmacological residues in animal products and thus reduce the problem of antibiotic resistance.
Reference Camerlink I, Ellinger L, Bakker EJ, Lantinga EA (2010). Homeopathy as replacement to antibiotics in the case of Escherichia coli diarrhoea in neonatal piglets. Homeopathy, 99; 57–62.
PubMed abstract can be found here, full article here: http://www.homeopathyeurope.org/media/news/homeopathy-as-an-alternative-to-antibiotics-in-diarrhoea-in-piglets
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Received 7 February 2011; revised 13 May 2011; Accepted 24 May 2011. Available online 28 September 2011.
Hyperthyroidism is a frequent veterinary problem, particularly in elderly cats. Homeopathic treatment and other integrative modalities were provided for four hyperthyroid cats whose owners did not want conventional treatment. Symptomatic homeopathic treatment with Thyroidinum was helpful in one cat. All cats were prescribed an appropriate individualized homeopathic remedy. All four cats showed resolution of clinical signs; three attained normal thyroid hormone levels. Three cats later received acupuncture and/or herbal medicines; two cats later received symptomatic homeopathic remedies. Two cats are thriving after over 3.5 and 4.25 years of treatment; two were euthanized for unrelated problems after 3 and 4 years of treatment. Homeopathic and complementary therapies avoid the potential side effects of methimazole and surgical thyroidectomy, they are less costly than radioactive iodine treatment, and they provide an option for clients who decline conventional therapies.
Keywords: Hyperthyroidism; Feline; Thyroidinum; Constitutional; Individualized; Veterinary; Homeopathy