Psorinum Therapy in Treating Stomach, Gall Bladder, Pancreatic, and Liver Cancers: A Prospective Clinical Study

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004411/?tool=pubmed
Hindawi Publishing Corporation
Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 724743, 7 pages
doi:10.1155/2011/724743
Psorinum Therapy in Treating Stomach, Gall Bladder, Pancreatic, and Liver Cancers: A Prospective Clinical Study

Aradeep Chatterjee,1* Jaydip Biswas,2 Ashim Chatterjee,1 Sudin Bhattacharya,2 Bishnu Mukhopadhyay,3 and Syamsundar Mandal2

1Critical Cancer Management Research Centre & Clinic, 381 S K Deb Road, West Bengal, Kolkata 700 048, India 2Chittaranjan National Cancer Institute, Kolkata 700 026, India 3National Institute of Technology, Durgapur 713209, India

*Aradeep Chatterjee: Email: arodeep@gmail.com

Abstract

We prospectively studied the clinical efficacy of an alternative cancer treatment "Psorinum Therapy" in treating stomach, gall bladder, pancreatic and liver cancers. Our study was observational, open level and single arm. The participants' eligibility criteria included histopathology/cytopathology confirmation of malignancy, inoperable tumor, and no prior chemotherapy or radiation therapy. The primary outcome measures of the study were (i) to assess the radiological tumor response (ii) to find out how many participants survived at least 1 year, 2 years, 3 years, 4 years and finally 5 years after the beginning of the study considering each type of cancer. Psorinum-6x was administered orally to all the participants up to 0.02ml/Kg body weight as a single dose in empty stomach per day for 2 years along with allopathic and homeopathic supportive cares. 158 participants (42 of stomach, 40 of gall bladder, 44 of pancreatic, 32 of liver) were included in the final analysis of the study. Complete tumor response occurred in 28 (17.72%) cases and partial tumor response occurred in 56 (35.44%) cases. Double-blind randomized controlled clinical trial should be conducted for further scientific exploration of this alternative cancer treatment.

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Hepatitis B vaccine induces apoptotic death in Hepa1-6 cells.

http://www.greenmedinfo.com/article/hepatitis-b-vaccine-induces-cell-death-liver-cells-and-mouse-liver
Abstract Title: 

Hepatitis B vaccine induces apoptotic death in Hepa1-6 cells. 

Abstract Source: 

Apoptosis. 2012 Jan 17. Epub 2012 Jan 17. PMID: 22249285 

Abstract Author(s): 

Heyam Hamza, Jianhua Cao, Xinyun Li, Changchun Li, Mengjin Zhu, Shuhong Zhao 

Article Affiliation: 

Key Lab of Agricultural Animal Genetics, Breeding, and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China, Heyam68_hamza@yahoo.com. Abstract: 

Vaccines can have adverse side-effects, and these are predominantly associated with the inclusion of chemical additives such as aluminum hydroxide adjuvant. The objective of this study was to establish an in vitro model system amenable to mechanistic investigations of cytotoxicity induced by hepatitis B vaccine, and to investigate the mechanisms of vaccine-induced cell death. The mouse liver hepatoma cell line Hepa1-6 was treated with two doses of adjuvanted (aluminium hydroxide) hepatitis B vaccine (0.5 and 1 μg protein per ml) and cell integrity was measured after 24, 48 and 72 h. Hepatitis B vaccine exposure increased cell apoptosis as detected by flow cytometry and TUNEL assay. Vaccine exposure was accompanied by significant increases in the levels of activated caspase 3, a key effector caspase inthe apoptosis cascade. Early transcriptional events were detected by qRT-PCR. We report that hepatitis B vaccine exposure resulted in significant upregulation of the key genes encoding caspase 7, caspase 9, Inhibitor caspase-activated DNase (ICAD), Rho-associated coiled-coil containing protein kinase 1 (ROCK-1), and Apoptotic protease activating factor 1 (Apaf-1). Upregulation of cleaved caspase 3,7 were detected by western blot in addition to Apaf-1 and caspase 9 expressions argues that cell death takes place via the intrinsic apoptotic pathway in which release of cytochrome c from the mitochondria triggers the assembly of a caspase activation complex. We conclude that exposure of Hepa1-6 cells to a low dose of adjuvanted hepatitis B vaccine leads to loss of mitochondrial integrity, apoptosis induction, and cell death, apoptosis effect was observed also in C2C12 mouse myoblast cell line after treated with low dose of vaccine (0.3, 0.1, 0.05 μg/ml). In addition In vivo apoptotic effect of hepatitis B vaccine was observed in mouse liver. 

Pubmed Data : Apoptosis. 2012 Jan 17. Epub 2012 Jan 17. PMID: 22249285 Article Published Date : Jan 17, 2012 Study Type : Animal Study

Modulation of Signal Proteins: A Plausible Mechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in Mice

Hindawi Publishing Corporation | Evidence-Based Complementary and Alternative Medicine | Volume 2011, Article ID 286320, 12 pagesModulation of Signal Proteins: A PlausibleMechanism to Explain How a Potentized Drug Secale Cor 30C Diluted beyond Avogadro's Limit Combats Skin Papilloma in MiceAnisur Rahman Khuda-Bukhsh,1 Soumya Sundar Bhattacharyya,1 Saili Paul,1 Suman Dutta,1 Naoual Boujedaini,2 and Philippe Belon2

1.Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, West Bengal, India 2.Boiron Laboratory, Lyon, France

Copyright © 2011 Anisur Rahman Khuda-Bukhsh et al. This is an open access article.

In homeopathy, ability of ultra-high diluted drugs at or above potency 12C (diluted beyond Avogadro's limit) in ameliorating/curing various diseases is often questioned, particularly because the mechanism of action is not precisely known. We tested the hypothesis if suitable modulations of signal proteins could be one of the possible pathways of action of a highly diluted homeopathic drug, Secale cornutum 30C (diluted 1060 times; Sec cor 30). It could successfully combat DMBA + croton oilinduced skin papilloma in mice as evidenced by histological, cytogenetical, immunofluorescence, ELISA and immunoblot findings. Critical analysis of several signal proteins like AhR, PCNA, Akt, Bcl-2, Bcl-xL, NF-κB and IL-6 and of pro-apoptotic proteins like cytochrome c, Bax, Bad, Apaf, caspase-3 and -9 revealed that Sec cor 30 suitably modulated their expression levels along with amelioration of skin papilloma. FACS data also suggested an increase of cell population at S and G2 phases and decrease in sub- G1 and G1 phages in carcinogen-treated drug-unfed mice, but these were found to be near normal in the Sec cor 30-fed mice. There was reduction in genotoxic and DNA damages in bone marrow cells of Sec Cor 30-fed mice, as revealed from cytogenetic and Comet assays. Changes in histological features of skin papilloma were noted. Immunofluorescence studies of AhR and PCNA also suggested reduced expression of these proteins in Sec cor 30-fed mice, thereby showing its anti-cancer potentials against skin papilloma. Furthermore, this study also supports the hypothesis that potentized homeopathic drugs act at gene regulatory level.

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n late 2011, the Swiss government's report on homeopathic medicine represents the most comprehensive evaluation of homeopathic medicine ever written by a government

The Swiss government has a long and widely-respected history of neutrality, and therefore, reports from this government on controversial subjects need to be taken more seriously than other reports from countries that are more strongly influenced by present economic and political constituencies. When one considers that two of the top five largest drug companies in the world have their headquarters in Switzerland, one might assume that this country would have a heavy interest in and bias toward conventional medicine, but such assumptions would be wrong.  In late 2011, the Swiss government's report on homeopathic medicine represents the most comprehensive evaluation of homeopathic medicine ever written by a government and was just published in book form in English (Bornhoft and Matthiessen, 2011). This breakthrough report affirmed that homeopathic treatment is both effective and cost-effective and that homeopathic treatment should be reimbursed by Switzerland's national health insurance program. 

The Swiss government's inquiry into homeopathy and complementary and alternative (CAM) treatments resulted from the high demand and widespread use of alternatives to conventional medicine in Switzerland, not only from consumers but from physicians as well. Approximately half of the Swiss population have used CAM treatments and value them. Further, about half of Swiss physicians consider CAM treatments to be effective. Perhaps most significantly, 85 percent of the Swiss population wants CAM therapies to be a part of their country's health insurance program. 

It is therefore not surprising that more than 50 percent of the Swiss population surveyed prefer a hospital that provides CAM treatments rather to one that is limited to conventional medical care. 

Beginning in 1998, the government of Switzerland decided to broaden its national health insurance to include certain complementary and alternative medicines, including homeopathic medicine, traditional Chinese medicine, herbal medicine, anthroposophic medicine, and neural therapy. This reimbursement was provisional while the Swiss government commissioned an extensive study on these treatments to determine if they were effective and cost-effective. The provisional reimbursement for these alternative treatments ended in 2005, but as a result of this new study, the Swiss government's health insurance program once again began to reimburse for homeopathy and select alternative treatments. In fact, as a result of a national referendum in which more than two-thirds of voters supported the inclusion of homeopathic and select alternative medicines in Switzerland's national health care insurance program, the field of complementary and alternative medicine has become a part of this government's constitution (Dacey, 2009; Rist, Schwabl, 2009). 

The Swiss Government's "Health Technology Assessment" 

The Swiss government's "Health Technology Assessment" on homeopathic medicine is much more comprehensive than any previous governmental report written on this subject to date. Not only did this report carefully and comprehensively review the body of evidence from randomized double-blind and placebo controlled clinical trials testing homeopathic medicines, they also evaluated the "real world effectiveness" as well as safety and cost-effectiveness. The report also conducted a highly-comprehensive review of the wide body of preclinical research (fundamental physio-chemical research, botanical studies, animal studies, and in vitro studies with human cells). 

And still further, this report evaluated systematic reviews and meta-analyses, outcome studies, and epidemiological research. This wide review carefully evaluated the studies conducted, both in terms of quality of design and execution (called "internal validity") and how appropriate each was for the way that homeopathy is commonly practiced (called "external validity"). The subject of external validity is of special importance because some scientists and physicians conduct research on homeopathy with little or no understanding of this type of medicine (some studies tested a homeopathic medicine that is rarely used for the condition tested, while others utilized medicines not commonly indicated for specific patients). When such studies inevitably showed that the homeopathic medicine did not "work," the real and accurate assessment must be that the studies were set up to disprove homeopathy... or simply, the study was an exploratory trial that sought to evaluate the results of a new treatment (exploratory trials of this nature are not meant to prove or disprove the system of homeopathy but only to evaluate that specific treatment for a person with a specific condition). 

After assessing pre-clinical basic research and the high quality clinical studies, the Swiss report affirmed that homeopathic high-potencies seem to induce regulatory effects (e.g., balancing or normalizing effects) and specific changes in cells or living organisms. The report also reported that 20 of the 22 systematic reviews of clinical research testing homeopathic medicines detected at least a trend in favor of homeopathy.* (Bornhöft, Wolf, von Ammon, et al, 2006) 

The Swiss report found a particularly strong body of evidence to support the homeopathic treatment of Upper Respiratory Tract Infections and Respiratory Allergies. The report cited 29 studies in "Upper Respiratory Tract Infections/AllergicReactions," of which 24 studies found a positive result in favor of homeopathy. Further, six out of seven controlled studies that compared homeopathic treatment with conventional medical treatment showed that homeopathy to be more effective than conventional medical interventions (the one other trial found homeopathic treatment to be equivalent to conventional medical treatment). All of these results from homeopathic treatment came without the side effects common to conventional drug treatment. In evaluating only the randomized placebo controlled trials, 12 out of 16 studies showed a positive result in favor of homeopathy. 

The authors of the Swiss government's report acknowledge that a part of the overall review of research included one review of clinical research in homeopathy (Shang, et al, 2005). However, the authors noted that this review of research has been widely and harshly criticized by both advocates and non-advocates of homeopathy. The Swiss report noted that the Shang team did not even adhere to the QUORUM guidelines which are widely recognized standards for scientific reporting (Linde, Jonas, 2005). The Shang team initially evaluated 110 homeopathic clinical trials and then sought to compare them with a matching 110 conventional medical trials. Shang and his team determined that there were 22 "high quality" homeopathic studies but only nine "high quality" conventional medical studies. Rather than compare these high quality trials (which would have shown a positive result for homeopathy), the Shang team created criteria to ignore a majority of high quality homeopathic studies, thereby trumping up support for their original hypothesis and bias that homeopathic medicines may not be effective (Lüdtke, Rutten, 2008). 

The Swiss report also notes that David Sackett, M.D., the Canadian physician who is widely considered to be one of the leading pioneers in "evidence based medicine," has expressed serious concern about those researchers and physicians who consider randomized and double-blind trials as the only means to determine whether a treatment is effective or not. To make this assertion, one would have to acknowledge that virtually all surgical procedures were "unscientific" or "unproven" because so few have undergone randomized double-blind trials. 

In my view, for a treatment to be determined to be "effective" or "scientifically proven," a much more comprehensive assessment of what works and doesn't is required. Ultimately, the Swiss government's report on homeopathy represents an evaluation of homeopathy that included an assessment of randomized double blind trials as well as other bodies of evidence, all of which together lead the report to determine that homeopathic medicines are indeed effective. 

The next article will discuss further evidence provided in this report from the Swiss government on the effectiveness and cost-effectiveness of homeopathic care. 

--- REFERENCES: 

Bornhoft, Gudrun, and Matthiessen, Peter F. Homeopathy in Healthcare: Effectiveness, Appropriateness, Safety, Costs. Goslar, Germany: Springer, 2011. http://rd.springer.com/book/10.1007/978-3-642-20638-2/page/1(This book is presently available from the German office of the publisher, and it will become available via the American office as well as select booksellers in mid- to late-February, 2012.)(NOTE: When specific facts in the above article are provided but not referenced, this means that these facts were derived from this book.) 

Bornhöft G, Wolf U, von Ammon K, Righetti M, Maxion-Bergemann S, Baumgartner S, Thurneysen AE, Matthiessen PF. Effectiveness, safety and cost-effectiveness of homeopathy in general practice - summarized health technology assessment. Forschende Komplementärmedizin (2006);13 Suppl 2:19-29. http://www.ncbi.nlm.nih.gov/pubmed/16883077 

Dacey, Jessica. Therapy supporters roll up sleeves after vote. SwissInfo.ch, May 19, 2009. http://www.swissinfo.ch/eng/politics/Therapy_supporters_roll_up_sleeves_after_vote.html?cid=670064 

Linde K, Jonas W. Are the clinical effects of homeopathy placebo effects? Lancet 36:2081-2082. DOI:10.1016/S0140-6736(05)67878-6. http://download.thelancet.com/pdfs/journals/lancet/PIIS0140673605678786.pdf 

Lüdtke R, Rutten ALB. The conclusions on the effectiveness of homeopathy highly depend on the set of analysed trials. Journal of Clinical Epidemiology. October 2008. doi: 10.1016/j.jclinepi.2008.06/015. http://www.jclinepi.com/article/S0895-4356(08)00190-X/abstract 

Rist L, Schwabl H: Komplementärmedizin im politischen Prozess. Schweizer Bevölkerungstimmt über Verfassungsartikel «Zukunft mit Komplementärmedizin» ab. Forsch Komplementmed 2009, doi 10.1159/000203073. (Translation: Complementary medicine in the political process: The Swiss population votes on the Constitutional Article "The future with complementary medicine" http://www.ayurveda-association.eu/files/swiss_referendum_on_cam_-_forschkomplementmed_2009.pdf 

*Although this Swiss government report was just published in book form in 2011, the report was finalized in 2006. In light of this date, the authors evaluated systematic reviews and meta-analyses on homeopathic research up until June 2003. 

By, Dana Ullman, MPH, is America's leading spokesperson for homeopathy and is the founder of www.homeopathic.com. He is the author of 10 books, including his bestseller, Everybody's Guide to Homeopathic Medicines. His most recent book is, The Homeopathic Revolution: Why Famous People and Cultural Heroes Choose Homeopathy (the Foreword to this book was written by Dr. Peter Fisher, the Physician to Her Majesty Queen Elizabeth II). Dana lives, practices, and writes from Berkeley, California. 

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[Fwd: [HOMEOPATHY] Who is more neutral than the Swiss...]

Who is more neutral than the Swiss...
Dana Ullman 6:40am Feb 15
Who is more neutral than the Swiss government...and this is the most positive report on homeopathy ever published by a government! This is great news...spread the good news! http://www.huffingtonpost.com/dana-ullman/homeopathic-medicine-_b_1258607.html?ref=health-and-fitness&ir=Health+and+Fitness
The Swiss Government's Remarkable Report on Homeopathic Medicine

www.huffingtonpost.com
The Swiss government's report on homeopathic medicine represents the most comprehensive evaluation o...

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Meningococcal Meningitis in Brazil

The Brazilian ExperienceIn 1998 there was an outbreak of meningococcal meningitis in a region of Brazil. Many doctors in that country are also homeopaths. There was no vaccine available at the time, so a group of doctors who worked in the region used the meningococcal Nosode to immunize 65,826 children. Another 23,539 children in the region were not immunized. The doctors followed the two groups for 12 months. After 6 months the efficacy of homeoprophylaxis was 95%, and after 12 months was 91%. A complete and statistically rigorous report was published in a leading peer reviewed Homeopathic journal, and is available for study (see reference following). Mroninski C, Adriano E, Mattos G (2001) Meningococcinum: Its protective effect against meningococcal disease. Homoeopathic Links Winter Vol 14(4); pp. 230-4. 

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What is common in Rheumatoid arthritis, Multiple Sclerosis, Depression and Osteoporosis?

What is common in Rheumatoid arthritis, Multiple Sclerosis, Depression and Osteoporosis? These are diseases more prevalent in females; other than the diseases of female reproductive system which make up a large section (that’s the reason we have a different subject of Obstetrics and Gynaecology) there are some diseases which are predominantly found in females.

The statistics of diseases in females is overwhelming -

  • Autoimmune diseases affect approximately 8% of the population, 78% of whom are women. Female/Male Ratios in some Autoimmune Diseases are:
    DISEASE RATIO
    Hashimoto's disease 50:1
    Systemic lupus erythematosus 9:1
    Chronic active hepatitis 8:1
    Graves' disease 7:1
    Type I diabetes 2:1
    Rheumatoid arthritis 4:1
    Scleroderma 3:1
    Myasthenia gravis 2:1
    Multiple sclerosis 2:1

    (From the American Autoimmune Related Diseases Association, Michigan National Bank Building, 15475 Granot Ave, Detroit, MI 48205, (313) 371-8600.)

  • A survey conducted by a study released by the Associated Chamber of Commerce and Industry said that 68% of working women surveyed within the age group of 21 to 52 years were suffering from lifestyle diseases.
  • Cardiovascular disease (CVD) is the number one killer of women across the world - it kills more of them each year than all cancers, tuberculosis, HIV/AIDS and malaria combined.
  • Unipolar depression, predicted to be the second leading cause of global disability burden by 2020, is twice as common in women.

These diseases are predominantly found in females; some have a link to female gene pattern, others to hormonal changes and some to female body structure while some are linked to the female psyche and lifestyle.

Now in all of the above factors, it is only the psyche and lifestyle which requires more attention as body structure and gene pattern cannot be changed while lifestyle and psyche can be.

Lifestyle diseases characterize those diseases whose occurrence is primarily based on the daily habits of people and are a result of an inappropriate relationship of people with their environment. The main factors contributing to lifestyle diseases include bad food habits, physical inactivity, wrong body posture, and disturbed biological clock. According to a survey conducted by the Associated Chamber of Commerce and Industry (ASSOC-HAM), 68% of working women in the age bracket of 21-52 years were found to be afflicted with lifestyle ailments such as obesity, depression, chronic backache, diabetes and hypertension.

Women play multiple roles- specially working women who have to balance between work and home resulting in negligence of their own health. Tight deadlines, work pressures, social networking, travel, etc. are just some of the common reasons of an increase in lifestyle ailments like obesity, depression, diabetes, blood pressure, etc. Today women tend to give more importance to their careers rather than their own health. Work pressures lead them to eat more of junk food which leads to obesity and other health related issues. Lack of time forces them to get less amount and poor quality of sleep. A busy lifestyle results in lack of exercise and poor nutrition resulting in iron and calcium deficiency. Irritation and mental depression become a part of their lives which in turn badly affects the hormones that play a vital role in a woman’s body. Hormonal disturbances are increased with stress and then result in ovulation and polycystic ovarian diseases. The study 'Preventive Healthcare and Corporate Female Workforce' also said that long hours and working under strict deadlines cause up to 75% of working women to suffer from depression or general anxiety disorder, compared to women with lesser levels of psychological demand at work. The study cited scientific evidence that healthy diet and adequate physical activity - at least 30 minutes of moderate activity at least five days a week - helped prevent NCDs.

Gender differences exist in patterns of help seeking for psychological disorder. Women are more likely to seek help from and disclose mental health problems to their primary health care physician while men are more likely to seek specialist mental health care and are the principal users of inpatient care.

There is a need to focus our attention on preventive health care. Lack of exercise, poor nutrition, exposure to sunlight and pollutants are the main causes of obesity, malnutrition, hypertension and skin diseases. Excessive intake of alcohol, drug abuse, drug addiction, and internet addiction are also associated with the lifestyle diseases. Over indulgence or interest in internet may lead to internet addiction disorder (IAD), the most modern lifestyle disease. Ignorance about health care may have multiple implications on our health, behavior and attitude. Casual medication and poor compliance of medical advice add to the gravity of lifestyle diseases. Working couples in general and employed women in particular need to be health conscious to be healthy and more productive. They must have a time table with sufficient time for exercise, entertainment and grooming their health and beauty.

Brisk walking for 15 minutes daily may show promising results in obese, diabetics and hypertensive people as it improves blood circulation, removes lactic acid and uric acid, frees-up tight joints, relaxes the muscles, tones-up the body and removes blockages from the blood vessels. Brisk walking is also beneficial for maintaining good health and preventing lifestyle diseases. Some tips found to be beneficial for overcoming majority of lifestyle diseases are:

  1. Make a time table for daily activities with sufficient time for exercise and entertainment.
  2. Do brisk walking daily for 15 minutes or 10,000 steps or 2-3 kilometers.
  3. Practice meditation or Yoga for at least 30 minutes. A
  4. Avoid fried food stuffs and junk food. Avoid foods with preservatives and coloring agents
  5. Increase intake of fruits, salad, healthy and nutritious diet.
  6. Never skip a meal for efficiency and productivity.
  7. Have a good night sleep; also try to rest whenever your body demands it.
  8. Use proper seat and sit in a right posture at home and at workplace to avoid postural disorders like cervical sprain and backache.
  9. Periodic medical checkup.
  10. Follow medical advice if you have some health problem in addition to life style disorder.

Homeopathy as an alternative to antibiotics in diarrhoea in piglets

Homeopathy as an alternative to antibiotics in diarrhoea in pigletsA research study conducted at the Wageningen University in the Netherlands suggests that homeopathy may be an alternative to antibiotics in neonatal diarrhea of piglets.The overuse of antibiotics in poultry, beef cattle and swine production poses a serious threat to human health, animal health and the environment. Sustainable alternatives to antibiotics are desperately needed.

In the organic livestock sector antibiotics are preferably replaced by complementary or alternative medicines (CAM), of which homeopathy is the most frequently applied. Homeopathic treatment has significant benefits since there are no residues of homeopathic medicines in animal products, nor does homeopathy generate resistant microorganisms.

The Biological Farming Systems Group at the Wageningen University in the Netherlands recently conducted a research study to investigate if homeopathy might be an alternative to antibiotics in one of the most common illnesses in swine which is neonatal diarrhoea of piglets. This disease leads to weight loss and increased piglet mortality, which has substantial economic consequences. Conventional treatments of Escherichia coli (E. coli) diarrhoea is administration of antibiotics to affected piglets, or preventive vaccination of the sows.

To investigate if E. coli diarrhoea in neonatal piglets could be prevented by homeopathy, the researchers set up a randomised, observer blind and placebo-controlled trial. On a commercial pig farm 52 sows of different parities, in their last month of gestation, were treated twice a week with either the homeopathic agent Coli 30K or placebo. The 525 piglets born from these sows were scored for occurrence and duration of diarrhoea.

Piglets of the homeopathic treated group had significantly less E. coli diarrhoea than piglets in the placebo group (P < .0001). Especially piglets from first parity sows gave a good response to treatment with Coli 30K. The diarrhoea seemed to be less severe in the homeopathically treated litters, there was less transmission and duration appeared shorter.

Advantages at farm level are application of the treatment by the farmer and cost reduction. These advantages and the positive results from this study make the homeopathic agent Coli 30K an attractive potential alternative in the prevention of E. coli diarrhoea. This study also suggests that homeopathic treatment in livestock may help the European citizen be protected from pharmacological residues in animal products and thus reduce the problem of antibiotic resistance.

Reference Camerlink I, Ellinger L, Bakker EJ, Lantinga EA (2010). Homeopathy as replacement to antibiotics in the case of Escherichia coli diarrhoea in neonatal piglets. Homeopathy, 99; 57–62.

PubMed abstract can be found here, full article here: http://www.homeopathyeurope.org/media/news/homeopathy-as-an-alternative-to-antibiotics-in-diarrhoea-in-piglets

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Homeopathy Halts Cuban Epidemic Better Than Vaccines

Homeopathy Halts Cuban Epidemic Better Than Vaccines  Swamp fever, also known as leptospirosis, is a major problem in Cuba.  Each year, an epidemic of swamp fever plagues the island nation during the flood season when the illness is transferred from rats to people. 

The very serious symptoms of swamp fever include fever, diarrhea, vomiting, jaundice, meningitis, liver failure, renal damage, respiratory illness and in many cases, death. 

Fortunately for Cuba, Big Pharma is not much interested in monopoly control of its healthcare system which leaves the door open for alternative and nontoxic approaches to health to bloom. 

In this environment very open to homeopathy, the Finlay Institute, a Cuban research foundation, worked with Cuban doctors to develop a homeopathic nosode for swamp fever. 

The remedy was based on the homeopathic principle that “like cures like” and was developed and administered on a wide scale as a preventative treatment.  In 2008, 2.5 million people who were most susceptible to the disease were treated with 2 doses of the remedy seven to nine days apart.   The Cuban Ministry of Public Health implemented and managed the operation. 

The results of this effort were nothing short of spectacular. The typical rate of infection when vaccination and antibiotics are used is a few thousand cases per year including some deaths. 

When the homeopathic remedy was used, however, only ten cases of swamp fever were reported among the 2.5 million treated with the homeopathic nosode with no mortality of any hospitalized patients! 

The financial cost to the Cuban government for this astonishingly successful health campaign was only $200,000 compared with the $2,000,000 that would have been incurred for conventional vaccination and antibiotics. 

Not only was homeopathy clearly more effective than vaccines for preventing swamp fever, it was also a much more cost effective solution with no toxic side effects such as is the case with vaccination. 

Homeopathy for epidemics works.  There is no need for toxic and expensive vaccine injections which produce masses of auto-immune compromised children and adults alike in need and dependent upon – more drugs! 

The catalyst for widespread use of homeopathic nosodes as a safe and effective alternative to the ever growing list of toxic vaccines must come from parents, in particular mothers.  Mothers must refuse toxic vaccines for their children and demand this type of safe and effective remedy at a grassroots level as it will never come from the conventional medical establishment which has a strongly invested profit motive for keeping things the way they are. 

Sarah, The Healthy Home Economist 

http://www.thehealthyhomeeconomist.com/homeopathy-halts-cuban-epidemic-better-than-vaccines/

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“The information contained in this message is for educational purposes and constitutes a response to a private request for information only and does not constitute a solicitation for services and makes no claim or promise that any product or service that may cure any condition or ailment,”

The use of Arsenicum album 30c to complement conventional treatment of neonatal diarrhoea (‘scours’) in calves

S. Kayne PhD, MBA, BSC, MRPHARMS, MCPP, DAGVETPHARM, MPSNZ*Corresponding Author Contact Information, A. Rafferty BVMS, CERT CHP, CERT SHP, MRCVS**

Available online 5 September 2006.

Abstract

In a pilot double blind study carried out in Scotland, the effect of supplementing a conventional treatment plan with homoeopathic Arsenicum albumwas studied. In the management of neonatal calf scour it appeared that more animals recovered after one day in the group that had received active medicine, than in the placebo group. These results are encouraging.

Keywords: Scours; Arsenicum album; Calves; Diarrhoea; neonatal; Veterinary medicine

Corresponding Author Contact InformationAddress for correspondence Dr S. B. Kayne 79 Milverton Road Giffnock Glasgow G46 7LQ

*Lecturer in homoeopathic pharmacy, Academic Department of Homoeopathic Medicine, Glasgow Homoeopathic Hospital.

**Veterinary Surgeon.

Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions

Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions

J. Sainte-Laudy1Corresponding Author Contact InformationE-mail The Corresponding Author, Ph Belon2

 

Received 8 July 2009; revised 21 September 2009; Accepted 23 September 2009. Available online 27 November 2009.

Background

At the beginning of this series of experiments we were looking for a model based on the use of purified commercially available compounds based on a fully described and accepted pharmacological model to study of the biological effect of high dilutions. Negative feedback induced by histamine, a major pro-inflammatory mediator, on basophils and mast cells activation via an H2 receptor me these criteria. The simplest way of measuring basophil activation in the early 1980's was the human basophil activation test (HBDT).

Objectives

Our major goal was first to study the biological effect of centesimal histamine dilutions beyond the Avogadro limit, on the staining properties of human basophils activated by an allergen extract initially house dust mite, then an anti-IgE and N-formyl-Met-Leu-Phe (fMLP). Technical development over the 25 years of our work led us to replace the manual basophil counting by flow cytometry. The main advantages were automation and observer independence. Using this latter protocol our aim was to confirm the existence of this phenomenon and to check its specificity by testing, under the same conditions, inactive analogues of histamine and histamine antagonists. More recently, we developed an animal model (mouse basophils) to study the effect of histamine on histamine release.

Methods and results

For the HBDT model basophils were obtained by sedimentation of human blood taken on EDTA and stained with Alcian blue. Results were expressed in percentage activation. Histamine dilutions tested were freshly prepared in the lab by successive centesimal dilutions and vortexing. Water controls were prepared in the same way. For the flow cytometric protocol basophils were first labeled by an anti-IgE FITC (basophil marker) and an anti-CD63 (basophil activation marker). Results were expressed in percentage of CD63 positive basophils. Another flow cytometric protocol has been developed more recently, based on basophil labeling by anti-IgE FITC (fluorescein isothiocyanate) and anti-CD203 PE (another human basophil activation marker). Results were expressed in mean fluorescence intensity of the CD203c positive population (MFI-CD203c) and an activation index calculated by an algorithm. For the mouse basophil model, histamine was measured spectrofluorimetrically.

The main results obtained over 28 years of work was the demonstration of a reproducible inhibition of human basophil activation by high dilutions of histamine, the effect peaks in the range of 15–17CH. The effect was not significant when histamine was replaced by histidine (a histamine precursor) or cimetidine (histamine H2 receptor antagonist) was added to the incubation medium. These results were confirmed by flow cytometry. Using the latter technique, we also showed that 4-Methyl histamine (H2 agonist) induced a similar effect, in contrast to 1-Methyl histamine, an inactive histamine metabolite.

Using the mouse model, we showed that histamine high dilutions, in the same range of dilutions, inhibited histamine release.

Conclusions

Successively, using different models to study of human and murine basophil activation, we demonstrated that high dilutions of histamine, in the range of 15–17CH induce a reproducible biological effect. This phenomenon has been confirmed by a multi-center study using the HBDT model and by at least three independent laboratories by flow cytometry. The specificity of the observed effect was confirmed, versus the water controls at the same dilution level by the absence of biological activity of inactive compounds such as histidine and 1-Methyl histamine and by the reversibility of this effect in the presence of a histamine receptor H2 antagonist.

Keywords: Human basophil; Mouse basophil; High dilutions; Homoeopathy; Histamine; Flow cytometry; Histamine release; IL4 release

http://www.sciencedirect.com/science/article/pii/S1475491609000952

Homeopathic Arnica montana for post-tonsillectomy analgesia: a randomised placebo control trial

Homeopathic Arnica montana for post-tonsillectomy analgesia: a randomised placebo control trial A. Robertson1, R. Suryanarayanan2, Corresponding Author Contact Information, E-mail The Corresponding Author, A Banerjee3 Purchase 1 ENT Department, University Hospital of Wales, Cardiff, UK 2 ENT Department, Arrowe Park Hospital, Wirral, UK 3 ENT Department, Leicester Royal Infirmary, Leicester, UK Received 19 June 2006; revised 3 August 2006; Accepted 30 October 2006. Available online 14 January 2007.

Abstract Objective: To evaluate the efficacy of Homeopathic Arnica in reducing the morbidity following tonsillectomy

Methods: Randomised double blind, placebo controlled trial at a tertiary referral centre. 190 patients over the age of 18 undergoing tonsillectomy were randomised into intervention and control groups receiving either Arnica 30c or identical placebo, 2 tablets 6 times in the first post-operative day and then 2 tablets twice a day for the next 7 days. The primary outcome measure was the change in pain scores (visual analogue scale) recorded by the patient on a questionnaire over 14 days post-operatively; Secondary outcome measures were: analgesia consumption, visits to the GP or hospital, antibiotic usage, the day on which their swallowing returned to normal and the day on which they returned to work. Results: 111 (58.4%) completed questionnaires were available for analysis. The Arnica group had a significantly larger drop in pain score from day 1 to day 14 (28.3) compared to the placebo group (23.8) with p<0.05. The two groups did not differ significantly on analgesic consumption or any of the other secondary outcome measures (number of post-operative visits to GP, use of antibiotics and secondary haemorrhage readmissions).

Conclusion: The results of this trial suggest that Arnica montana given after tonsillectomy provides a small, but statistically significant, decrease in pain scores compared to placebo. Keywords: homeopathy; surgery; pain management; tonsillectomy