Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome.

http://www.ncbi.nlm.nih.gov/pubmed/24931748Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. Peckham EJ1, Relton C2, Raw J3, Walters C3, Thomas K2, Smith C3, Kapur K3, Said E3. Author information Abstract

Irritable bowel syndrome (IBS) is a chronic condition for which there is no consensus on the optimum treatment. Gastroenterology problems are some of the most common conditions treated by homeopaths, yet few trials have explored the effectiveness of individualised homeopathic treatment for IBS. A three-armed trial was conducted which compared: usual care, homeopathic treatment plus usual care and supportive listening plus usual care. The primary outcome was change in irritable bowel symptom severity score between baseline and 26 weeks, calculated using ANCOVA. An interim ANCOVA adjusted for baseline IBS severity, age and employment status found no statistically significant difference between the three arms. However, a post-hoc test comparing homeopathic treatment plus usual care to usual care alone found a statistically significant difference in favour of homeopathic treatment. In addition, 62.5 percent of patients in the homeopathic treatment arm (compared to 25.0 percent of those in the usual care arm), achieved a clinically relevant change in irritable bowel symptom severity score, which indicates a promising effect for homeopathic treatment, though these results should be interpreted with caution due to the low number of participants in the study.

Copyright © 2014 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved. KEYWORDS:

Attention control; Homeopathy; Irritable bowel syndrome; Randomised controlled trial

PMID: 24931748 [PubMed - indexed for MEDLINE]